LCD/NCD Portal
Automated World Health
NCD110.5
GRANULOCYTE TRANSFUSIONS
Effective Date of this Version
• This is a longstanding national coverage determination. The effective date of this version has not been posted.
Benefit Category
• Inpatient Hospital Services.
• Outpatient Hospital Services Incident to a Physician's Service.
• Physicians' Services.
• Note: This may not be an exhaustive list of all applicable Medicare benefit categories for this item or service.
Indications and Limitations of Coverage
• Granulocyte transfusions to patients suffering from severe infection and granulocytopenia are a covered service under Medicare.
• Granulocytopenia is usually identified as fewer than 500 granulocytes/mm 3 whole blood.
• Accepted indications for granulocyte transfusions include:
o Granulocytopenia with evidence of gram negative sepsis.
o Granulocytopenia in febrile patients with local progressive infections unresponsive to appropriate antibiotic therapy, thought to be due to gram negative organisms.